Human Phenotype Ontology China

Last uploaded: November 21, 2019
Preferred Name

Hepatoblastoma

Synonyms

Pediatric Embryonal Hepatoma

HEPATOBLASTOMA, MALIGNANT

HBL

Pediatric Hepatoblastoma

Hepatoblastoma

hepatoblastoma

Definitions

A malignant liver neoplasm that occurs almost exclusively in infants, although isolated cases in older children and adults have been reported. Grossly, hepatoblastoma is solid, well circumscribed, and more often solitary than multiple. Microscopically, most of the tumors are composed exclusively of immature hepatocytic elements. About a fourth of hepatoblastomas contain a stromal component that may be undifferentiated or develop into bone or cartilage. The treatment of choice for hepatoblastoma is surgical excision with adjuvant therapy. Liver transplantation is being increasingly used as well.

ID

http://purl.obolibrary.org/obo/NCIT_C3728

definition

A malignant liver neoplasm that occurs almost exclusively in infants, although isolated cases in older children and adults have been reported. Grossly, hepatoblastoma is solid, well circumscribed, and more often solitary than multiple. Microscopically, most of the tumors are composed exclusively of immature hepatocytic elements. About a fourth of hepatoblastomas contain a stromal component that may be undifferentiated or develop into bone or cartilage. The treatment of choice for hepatoblastoma is surgical excision with adjuvant therapy. Liver transplantation is being increasingly used as well.

has_exact_synonym

Pediatric Embryonal Hepatoma

HEPATOBLASTOMA, MALIGNANT

HBL

Pediatric Hepatoblastoma

Hepatoblastoma

hepatoblastoma

has_obo_namespace

mouse_pathology.ontology

id

NCIT:C3728

label

Hepatoblastoma

notation

NCIT:C3728

prefLabel

Hepatoblastoma

subClassOf

http://purl.obolibrary.org/obo/MPATH_352

http://purl.obolibrary.org/obo/NCIT_C7708

http://purl.obolibrary.org/obo/NCIT_C3264

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http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3728 National Cancer Institute Thesaurus LOOM
http://purl.bioontology.org/ontology/MEDLINEPLUS/C0206624 MedlinePlus Health Topics LOOM
http://purl.bioontology.org/ontology/ICD10CM/C22.2 International Classification of Diseases, Version 10 - Clinical Modification LOOM
http://purl.bioontology.org/ontology/OMIM/MTHU007922 Online Mendelian Inheritance in Man LOOM
http://purl.bioontology.org/ontology/MESH/D018197 Medical Subject Headings LOOM
http://purl.bioontology.org/ontology/ICD10/C22.2 International Classification of Diseases, Version 10 LOOM
http://purl.obolibrary.org/obo/DOID_687 Human Disease Ontology 123 LOOM