Preferred Name |
interleukin-10 |
Synonyms |
CSIF IL-10 cytokine synthesis inhibitory factor IL10 |
Definitions |
A class 2 cytokine, IL-10 type that is a translation product of the human IL10 gene or a 1:1 ortholog thereof. Active interleukin-10 inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T cells. Structurally, IL-10 is a protein of about 160 amino acids that contains four conserved cysteines involved in disulfide bonds. Category=gene. |
ID |
http://purl.obolibrary.org/obo/PR_000001471 |
comment |
Category=gene. |
database_cross_reference |
PANTHER:PTHR11585:SF1 |
definition |
A class 2 cytokine, IL-10 type that is a translation product of the human IL10 gene or a 1:1 ortholog thereof. Active interleukin-10 inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T cells. Structurally, IL-10 is a protein of about 160 amino acids that contains four conserved cysteines involved in disulfide bonds. |
has_exact_synonym |
CSIF IL-10 cytokine synthesis inhibitory factor IL10 |
has_obo_namespace |
protein |
id |
PR:000001471 |
label |
interleukin-10 |
notation |
PR:000001471 |
prefLabel |
interleukin-10 |
subClassOf |