Human Phenotype Ontology China

Last uploaded: November 21, 2019
Preferred Name

interleukin-10

Synonyms

CSIF

IL-10

cytokine synthesis inhibitory factor

IL10

Definitions

A class 2 cytokine, IL-10 type that is a translation product of the human IL10 gene or a 1:1 ortholog thereof. Active interleukin-10 inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T cells. Structurally, IL-10 is a protein of about 160 amino acids that contains four conserved cysteines involved in disulfide bonds. Category=gene.

ID

http://purl.obolibrary.org/obo/PR_000001471

comment

Category=gene.

database_cross_reference

PANTHER:PTHR11585:SF1

definition

A class 2 cytokine, IL-10 type that is a translation product of the human IL10 gene or a 1:1 ortholog thereof. Active interleukin-10 inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T cells. Structurally, IL-10 is a protein of about 160 amino acids that contains four conserved cysteines involved in disulfide bonds.

has_exact_synonym

CSIF

IL-10

cytokine synthesis inhibitory factor

IL10

has_obo_namespace

protein

id

PR:000001471

label

interleukin-10

notation

PR:000001471

prefLabel

interleukin-10

subClassOf

http://purl.obolibrary.org/obo/PR_000001335

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