loading...| Preferred Name |
signal transduction |
| Synonyms |
signal transduction by conformational transition signal transduction by cis-phosphorylation signalling pathway signal transduction by trans-phosphorylation signaling pathway signal transduction by protein phosphorylation signalling cascade signaling cascade |
| Definitions |
Note that signal transduction is defined broadly to include a ligand interacting with a receptor, downstream signaling steps and a response being triggered. A change in form of the signal in every step is not necessary. Note that in many cases the end of this process is regulation of the initiation of transcription. Note that specific transcription factors may be annotated to this term, but core/general transcription machinery such as RNA polymerase should not. The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell. |
| ID |
http://purl.obolibrary.org/obo/GO_0007165 |
| comment |
Note that signal transduction is defined broadly to include a ligand interacting with a receptor, downstream signaling steps and a response being triggered. A change in form of the signal in every step is not necessary. Note that in many cases the end of this process is regulation of the initiation of transcription. Note that specific transcription factors may be annotated to this term, but core/general transcription machinery such as RNA polymerase should not. |
| database_cross_reference |
Wikipedia:Signal_transduction |
| has participant |
http://purl.obolibrary.org/obo/PR_P42684 http://purl.obolibrary.org/obo/PR_P10275 http://purl.obolibrary.org/obo/PR_P11802 http://purl.obolibrary.org/obo/PR_P42345 http://purl.obolibrary.org/obo/PR_P30530 http://purl.obolibrary.org/obo/PR_P04150 http://purl.obolibrary.org/obo/PR_P01189 http://purl.obolibrary.org/obo/PR_P20309 http://purl.obolibrary.org/obo/PR_P03372 http://purl.obolibrary.org/obo/PR_O75469 http://purl.obolibrary.org/obo/PR_Q9UM73 http://purl.obolibrary.org/obo/PR_Q92731 http://purl.obolibrary.org/obo/PR_O60760 http://purl.obolibrary.org/obo/PR_P10721 http://purl.obolibrary.org/obo/PR_P49069 http://purl.obolibrary.org/obo/PR_P06401 http://purl.obolibrary.org/obo/PR_P12931 http://purl.obolibrary.org/obo/PR_P11274 http://purl.obolibrary.org/obo/PR_P35348 http://purl.obolibrary.org/obo/PR_Q16539 http://purl.obolibrary.org/obo/PR_Q15125 http://purl.obolibrary.org/obo/PR_P09619 http://purl.obolibrary.org/obo/PR_P28472 http://purl.obolibrary.org/obo/PR_P07948 http://purl.obolibrary.org/obo/PR_Q02750 http://purl.obolibrary.org/obo/PR_P07333 http://purl.obolibrary.org/obo/PR_P17405 http://purl.obolibrary.org/obo/PR_P09038 http://purl.obolibrary.org/obo/PR_P08235 http://purl.obolibrary.org/obo/PR_P11229 |
| has_alternative_id |
GO:0023015 GO:0023014 GO:0023033 GO:0023016 GO:0023045 |
| has_narrow_synonym |
signal transduction by conformational transition signal transduction by cis-phosphorylation signal transduction by trans-phosphorylation signal transduction by protein phosphorylation signalling cascade signaling cascade |
| has_obo_namespace |
biological_process |
| has_related_synonym |
signalling pathway signaling pathway |
| id |
GO:0007165 |
| imported from | |
| in subset |
http://purl.oboInOwllibrary.org/oboInOwl/go#goslim_generic http://purl.oboInOwllibrary.org/oboInOwl/go#goslim_chembl http://purl.oboInOwllibrary.org/oboInOwl/go#goslim_plant http://purl.oboInOwllibrary.org/oboInOwl/go#goslim_metagenomics http://purl.oboInOwllibrary.org/oboInOwl/go#goslim_candida http://purl.oboInOwllibrary.org/oboInOwl/go#goslim_aspergillus |
| label |
signal transduction |
| notation |
GO:0007165 |
| prefLabel |
signal transduction |
| textual definition |
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell. |
| subClassOf |