Preferred Name

regulation of gene expression

Synonyms

regulation of gene product expression

regulation of protein expression

Definitions

Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form. This class covers any process that regulates the rate of production of a mature gene product, and so includes processes that regulate that rate by regulating the level, stability or availability of intermediates in the process of gene expression. For example, it covers any process that regulates the level, stability or availability of mRNA or circRNA for translation and thereby regulates the rate of production of the encoded protein via translation.

ID

http://purl.obolibrary.org/obo/GO_0010468

comment

This class covers any process that regulates the rate of production of a mature gene product, and so includes processes that regulate that rate by regulating the level, stability or availability of intermediates in the process of gene expression. For example, it covers any process that regulates the level, stability or availability of mRNA or circRNA for translation and thereby regulates the rate of production of the encoded protein via translation.

database_cross_reference

Wikipedia:Regulation_of_gene_expression

has_narrow_synonym

regulation of protein expression

has_obo_namespace

biological_process

has_related_synonym

regulation of gene product expression

id

GO:0010468

imported from

http://purl.obolibrary.org/obo/go.owl

label

regulation of gene expression

notation

GO:0010468

prefLabel

regulation of gene expression

textual definition

Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.

subClassOf

http://purl.obolibrary.org/obo/GO_0060255

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http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16609 National Cancer Institute Thesaurus LOOM
http://purl.org/obo/owl/GO#GO_0010468 MicroRNA Ontology LOOM
http://purl.obolibrary.org/obo/GO_0010468 Human Phenotype Ontology China LOOM
http://purl.obolibrary.org/obo/GO_0010468 Human Phenotype Ontology China SAME_URI
http://purl.obolibrary.org/obo/GO_0010468 Phenotypic Quality Ontology LOOM
http://purl.obolibrary.org/obo/GO_0010468 Phenotypic Quality Ontology SAME_URI
http://purl.obolibrary.org/obo/GO_0010468 Cell Ontology LOOM
http://purl.obolibrary.org/obo/GO_0010468 Cell Ontology SAME_URI
http://purl.obolibrary.org/obo/GO_0010468 Gene Ontology LOOM
http://purl.obolibrary.org/obo/GO_0010468 Gene Ontology SAME_URI
http://purl.obolibrary.org/obo/GO_0010468 Evidence and Conclusion Ontology LOOM
http://purl.obolibrary.org/obo/GO_0010468 Evidence and Conclusion Ontology SAME_URI