Medical Subject Headings

Last uploaded: November 5, 2019

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Preferred Name	Nicotine
Synonyms	Pyridine, 3-(1-methyl-2-pyrrolidinyl)-, (S)-
Definitions	Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
ID	http://purl.bioontology.org/ontology/MESH/D009538
altLabel	Pyridine, 3-(1-methyl-2-pyrrolidinyl)-, (S)- Nicotine Tartrate Nicotine Bitartrate
AQL	AA AD AE AG AI AN BI BL CF CH CL CS EC GE HI IM IP ME PD PK PO RE SD ST TO TU UR
cui	C0028042 C0028040
DC	1
definition	Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
DX	19660101
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000528 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000031 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000627
Inverse of RB	R7M676M8YV 6M3C89ZY6R
Inverse of RO	http://purl.bioontology.org/ontology/MESH/D014026
Inverse of SIB	http://purl.bioontology.org/ontology/MESH/D014049 http://purl.bioontology.org/ontology/MESH/D000068296 http://purl.bioontology.org/ontology/MESH/D015632 http://purl.bioontology.org/ontology/MESH/D010848 http://purl.bioontology.org/ontology/MESH/D002211 http://purl.bioontology.org/ontology/MESH/D000077613 http://purl.bioontology.org/ontology/MESH/D004095 http://purl.bioontology.org/ontology/MESH/D019469 http://purl.bioontology.org/ontology/MESH/D011728 http://purl.bioontology.org/ontology/MESH/D058924 http://purl.bioontology.org/ontology/MESH/D009286 http://purl.bioontology.org/ontology/MESH/D010632 http://purl.bioontology.org/ontology/MESH/D014053 http://purl.bioontology.org/ontology/MESH/D008797 http://purl.bioontology.org/ontology/MESH/D000631 http://purl.bioontology.org/ontology/MESH/D002243 http://purl.bioontology.org/ontology/MESH/D015082 http://purl.bioontology.org/ontology/MESH/D012992 http://purl.bioontology.org/ontology/MESH/D004115 http://purl.bioontology.org/ontology/MESH/D011746 http://purl.bioontology.org/ontology/MESH/D001621 http://purl.bioontology.org/ontology/MESH/D014311 http://purl.bioontology.org/ontology/MESH/D007539 http://purl.bioontology.org/ontology/MESH/D011805 http://purl.bioontology.org/ontology/MESH/D010847 http://purl.bioontology.org/ontology/MESH/D014331 http://purl.bioontology.org/ontology/MESH/D004319 http://purl.bioontology.org/ontology/MESH/D003007 http://purl.bioontology.org/ontology/MESH/D000069446 http://purl.bioontology.org/ontology/MESH/D004206 http://purl.bioontology.org/ontology/MESH/D000069582 http://purl.bioontology.org/ontology/MESH/D000077334 http://purl.bioontology.org/ontology/MESH/D019829 http://purl.bioontology.org/ontology/MESH/D011726 http://purl.bioontology.org/ontology/MESH/D009539 http://purl.bioontology.org/ontology/MESH/D000077786 http://purl.bioontology.org/ontology/MESH/D000069604 http://purl.bioontology.org/ontology/MESH/D053799 http://purl.bioontology.org/ontology/MESH/D009540 http://purl.bioontology.org/ontology/MESH/D001533 http://purl.bioontology.org/ontology/MESH/D011144
isa	http://purl.bioontology.org/ontology/MESH/D018722 http://purl.bioontology.org/ontology/MESH/D000077444 http://purl.bioontology.org/ontology/MESH/D005731
Mapped from	http://purl.bioontology.org/ontology/MESH/C002962 http://purl.bioontology.org/ontology/MESH/C049543 http://purl.bioontology.org/ontology/MESH/C098439 http://purl.bioontology.org/ontology/MESH/C507707 http://purl.bioontology.org/ontology/MESH/C000619734 http://purl.bioontology.org/ontology/MESH/C010062 http://purl.bioontology.org/ontology/MESH/C087868 http://purl.bioontology.org/ontology/MESH/C097951 http://purl.bioontology.org/ontology/MESH/C042938 http://purl.bioontology.org/ontology/MESH/C074420 http://purl.bioontology.org/ontology/MESH/C471911 http://purl.bioontology.org/ontology/MESH/C070297 http://purl.bioontology.org/ontology/MESH/C522876 http://purl.bioontology.org/ontology/MESH/C512814 http://purl.bioontology.org/ontology/MESH/C430747 http://purl.bioontology.org/ontology/MESH/C539942 http://purl.bioontology.org/ontology/MESH/C063738 http://purl.bioontology.org/ontology/MESH/C450043 http://purl.bioontology.org/ontology/MESH/C008614 http://purl.bioontology.org/ontology/MESH/C012419 http://purl.bioontology.org/ontology/MESH/C506430 http://purl.bioontology.org/ontology/MESH/C085795 http://purl.bioontology.org/ontology/MESH/C090027 http://purl.bioontology.org/ontology/MESH/C507706 http://purl.bioontology.org/ontology/MESH/C005311 http://purl.bioontology.org/ontology/MESH/C000621211 http://purl.bioontology.org/ontology/MESH/C047661 http://purl.bioontology.org/ontology/MESH/C050752 http://purl.bioontology.org/ontology/MESH/C034629 http://purl.bioontology.org/ontology/MESH/C024270 http://purl.bioontology.org/ontology/MESH/C025609 http://purl.bioontology.org/ontology/MESH/C000612708 http://purl.bioontology.org/ontology/MESH/C512816 http://purl.bioontology.org/ontology/MESH/C582060 http://purl.bioontology.org/ontology/MESH/C515996 http://purl.bioontology.org/ontology/MESH/C467228 http://purl.bioontology.org/ontology/MESH/C502317 http://purl.bioontology.org/ontology/MESH/C503244 http://purl.bioontology.org/ontology/MESH/C084131 http://purl.bioontology.org/ontology/MESH/C487835 http://purl.bioontology.org/ontology/MESH/C403088 http://purl.bioontology.org/ontology/MESH/C510953 http://purl.bioontology.org/ontology/MESH/C507705 http://purl.bioontology.org/ontology/MESH/C013129 http://purl.bioontology.org/ontology/MESH/C045981 http://purl.bioontology.org/ontology/MESH/C504259 http://purl.bioontology.org/ontology/MESH/C464971 http://purl.bioontology.org/ontology/MESH/C081694 http://purl.bioontology.org/ontology/MESH/C000588574 http://purl.bioontology.org/ontology/MESH/C515997
MDA	19990101
MMR	20180410
MN	D03.383.725.518 D03.132.760.570
notation	D009538
PA	D018722 D005731 D000077444
prefLabel	Nicotine
RR	R7M676M8YV 54-11-5
TERMUI	T028417 T028419 T028418
TH	FDA SRS (2014) FDA SRS (2015) UNK (19XX) USAN (19XX) NLM (1966) INN (19XX)
tui	T109 T131 T121
subClassOf	http://purl.bioontology.org/ontology/MESH/D011725 http://purl.bioontology.org/ontology/MESH/D012991

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Mapping To	Ontology	Source
http://purl.bioontology.org/ontology/LNC/MTHU003222	Logical Observation Identifier Names and Codes	CUI
http://purl.bioontology.org/ontology/LNC/MTHU003222	Logical Observation Identifier Names and Codes	LOOM
http://purl.obolibrary.org/obo/CHEBI_18723	Chemical Entities of Biological Interest Ontology	LOOM
http://purl.obolibrary.org/obo/CHEBI_18723	Human Phenotype Ontology China	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C691	National Cancer Institute Thesaurus	LOOM
http://purl.bioontology.org/ontology/MEDLINEPLUS/C0028040	MedlinePlus Health Topics	CUI
http://purl.bioontology.org/ontology/MEDLINEPLUS/C0028040	MedlinePlus Health Topics	LOOM
http://purl.bioontology.org/ontology/LNC/LP16219-5	Logical Observation Identifier Names and Codes	CUI
http://purl.bioontology.org/ontology/LNC/LP16219-5	Logical Observation Identifier Names and Codes	LOOM