Medical Subject Headings

Last uploaded: November 5, 2019
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Preferred Name

Renin
Synonyms

Inactive Renin
Definitions

A highly specific (Leu-Leu) endopeptidase that generates ANGIOTENSIN I from its precursor ANGIOTENSINOGEN, leading to a cascade of reactions which elevate BLOOD PRESSURE and increase sodium retention by the kidney in the RENIN-ANGIOTENSIN SYSTEM. The enzyme was formerly listed as EC 3.4.99.19.
ID

http://purl.bioontology.org/ontology/MESH/D012083
altLabel

Inactive Renin

Preprorenin

Pre Prorenin

Renin, Inactive

Angiotensinogenase

Angiotensin Forming Enzyme

Pre-Prorenin

Big Renin

Cryorenin

Angiotensin-Forming Enzyme

Renin, Big

Prorenin
AN

do not confuse with RENNIN see CHYMOSIN
AQL

AD AE AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
cui

C0072249

C0071937

C0035094
DC

1
definition

A highly specific (Leu-Leu) endopeptidase that generates ANGIOTENSIN I from its precursor ANGIOTENSINOGEN, leading to a cascade of reactions which elevate BLOOD PRESSURE and increase sodium retention by the kidney in the RENIN-ANGIOTENSIN SYSTEM. The enzyme was formerly listed as EC 3.4.99.19.
DX

19630101
HN

1963; for PRORENIN use RENIN (NM) 1977-2003, for PREPRORENIN use RENIN (NM) 1980-2003
Inverse of AQ

http://purl.bioontology.org/ontology/MESH/Q000032

http://purl.bioontology.org/ontology/MESH/Q000138

http://purl.bioontology.org/ontology/MESH/Q000737

http://purl.bioontology.org/ontology/MESH/Q000493

http://purl.bioontology.org/ontology/MESH/Q000145

http://purl.bioontology.org/ontology/MESH/Q000506

http://purl.bioontology.org/ontology/MESH/Q000187

http://purl.bioontology.org/ontology/MESH/Q000096

http://purl.bioontology.org/ontology/MESH/Q000037

http://purl.bioontology.org/ontology/MESH/Q000134

http://purl.bioontology.org/ontology/MESH/Q000592

http://purl.bioontology.org/ontology/MESH/Q000528

http://purl.bioontology.org/ontology/MESH/Q000008

http://purl.bioontology.org/ontology/MESH/Q000235

http://purl.bioontology.org/ontology/MESH/Q000648

http://purl.bioontology.org/ontology/MESH/Q000276

http://purl.bioontology.org/ontology/MESH/Q000191

http://purl.bioontology.org/ontology/MESH/Q000633

http://purl.bioontology.org/ontology/MESH/Q000652

http://purl.bioontology.org/ontology/MESH/Q000009

http://purl.bioontology.org/ontology/MESH/Q000302

http://purl.bioontology.org/ontology/MESH/Q000502

http://purl.bioontology.org/ontology/MESH/Q000494

http://purl.bioontology.org/ontology/MESH/Q000266

http://purl.bioontology.org/ontology/MESH/Q000600

http://purl.bioontology.org/ontology/MESH/Q000378

http://purl.bioontology.org/ontology/MESH/Q000172

http://purl.bioontology.org/ontology/MESH/Q000097

http://purl.bioontology.org/ontology/MESH/Q000627
Inverse of RB

EC 3.4.23.15

EC 3.4.23.-
Inverse of RO

http://purl.bioontology.org/ontology/MESH/D007606
Inverse of SIB

http://purl.bioontology.org/ontology/MESH/D045702

http://purl.bioontology.org/ontology/MESH/D002402

http://purl.bioontology.org/ontology/MESH/D010434

http://purl.bioontology.org/ontology/MESH/D045706

http://purl.bioontology.org/ontology/MESH/D000072396

http://purl.bioontology.org/ontology/MESH/D012085

http://purl.bioontology.org/ontology/MESH/D043423

http://purl.bioontology.org/ontology/MESH/D025901

http://purl.bioontology.org/ontology/MESH/D000071449

http://purl.bioontology.org/ontology/MESH/D016333

http://purl.bioontology.org/ontology/MESH/D045664

http://purl.bioontology.org/ontology/MESH/D043424

http://purl.bioontology.org/ontology/MESH/D045683

http://purl.bioontology.org/ontology/MESH/D020059
Machine permutation

1963; PRORENIN was listed under ENZYME PRECUSORS & RENIN 1977-2003; PREPRORENIN was listed under ENZYME PRECUSORS & RENIN 1980-2003
Mapped from

http://purl.bioontology.org/ontology/MESH/C567760

http://purl.bioontology.org/ontology/MESH/C535029

http://purl.bioontology.org/ontology/MESH/C070403

http://purl.bioontology.org/ontology/MESH/C037246

http://purl.bioontology.org/ontology/MESH/C562214

http://purl.bioontology.org/ontology/MESH/C473112

http://purl.bioontology.org/ontology/MESH/C000595796

http://purl.bioontology.org/ontology/MESH/C057629

http://purl.bioontology.org/ontology/MESH/C070714
MDA

19990101
MMR

20090706
MN

D08.811.277.656.837.750

D08.811.277.656.300.048.780

D08.811.277.656.074.500.780
notation

D012083
prefLabel

Renin
RR

80965-96-4 (CRN)
TERMUI

T035938

T035936

T091609

T091610

T035937

T091611

T112819

T112818

T091608
TH

NLM (2004)

NLM (1991)

NLM (1966)
tui

T116

T126

T123
subClassOf

http://purl.bioontology.org/ontology/MESH/D043484

http://purl.bioontology.org/ontology/MESH/D016282
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http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C113591 National Cancer Institute Thesaurus LOOM
http://purl.obolibrary.org/obo/PR_000013883 Human Phenotype Ontology China LOOM
http://purl.obolibrary.org/obo/PR_000013883 International Classification of Diseases Ontology LOOM
http://purl.obolibrary.org/obo/PR_000013883 Protein Ontology LOOM
http://purl.bioontology.org/ontology/LNC/LP32149-4 Logical Observation Identifier Names and Codes CUI
http://purl.bioontology.org/ontology/LNC/LP32149-4 Logical Observation Identifier Names and Codes LOOM
http://purl.bioontology.org/ontology/LNC/MTHU002548 Logical Observation Identifier Names and Codes CUI
http://purl.bioontology.org/ontology/OMIM/179820 Online Mendelian Inheritance in Man LOOM
http://purl.bioontology.org/ontology/LNC/LP15273-3 Logical Observation Identifier Names and Codes CUI
http://purl.bioontology.org/ontology/LNC/LP15273-3 Logical Observation Identifier Names and Codes LOOM
http://purl.bioontology.org/ontology/LNC/MTHU003186 Logical Observation Identifier Names and Codes CUI
http://purl.bioontology.org/ontology/LNC/MTHU003186 Logical Observation Identifier Names and Codes LOOM
http://purl.bioontology.org/ontology/LNC/LP15159-4 Logical Observation Identifier Names and Codes CUI