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A malignant tumor arising from the nuclear layer of the retina that is the most common primary tumor of the eye in children. The tumor tends to occur in early childhood or infancy and may be present at birth. The majority are sporadic, but the condition may be transmitted as an autosomal dominant trait. Histologic features include dense cellularity, small round polygonal cells, and areas of calcification and necrosis. An abnormal pupil reflex (leukokoria); NYSTAGMUS, PATHOLOGIC; STRABISMUS; and visual loss represent common clinical characteristics of this condition. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2104)
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Retinal Glioblastomas Retinoblastomas Retinoblastoma, Hereditary Retinal Neuroblastomas Hereditary Retinoblastomas Retinal Gliomas Retinal Neuroblastoma Neuroblastomas, Retinal Cancer, Retinoblastoma Eye Familial Retinoblastoma Retinoblastoma Eye Cancers Cancers, Retinoblastoma Eye Sporadic Retinoblastomas Glioblastomas, Retinal Retinal Glioblastoma Eye Cancer, Retinoblastoma Eye Cancers, Retinoblastoma Retinoblastoma, Sporadic Gliomas, Retinal Retinoblastoma Eye Cancer Neuroblastoma, Retinal Retinoblastomas, Familial Retinoblastomas, Sporadic Sporadic Retinoblastoma Retinal Glioma Familial Retinoblastomas Retinoblastomas, Hereditary Retinoblastoma, Familial Glioblastoma, Retinal Hereditary Retinoblastoma Glioma, Retinal
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| definition |
A malignant tumor arising from the nuclear layer of the retina that is the most common primary tumor of the eye in children. The tumor tends to occur in early childhood or infancy and may be present at birth. The majority are sporadic, but the condition may be transmitted as an autosomal dominant trait. Histologic features include dense cellularity, small round polygonal cells, and areas of calcification and necrosis. An abnormal pupil reflex (leukokoria); NYSTAGMUS, PATHOLOGIC; STRABISMUS; and visual loss represent common clinical characteristics of this condition. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2104)
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