loading...| Preferred Name |
Bone Remodeling |
| Synonyms |
Turnover, Bone |
| Definitions |
The continuous turnover of BONE MATRIX and mineral that involves first an increase in BONE RESORPTION (osteoclastic activity) and later, reactive BONE FORMATION (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium HOMEOSTASIS. An imbalance in the regulation of bone remodeling's two contrasting events, bone resorption and bone formation, results in many of the metabolic bone diseases, such as OSTEOPOROSIS. |
| ID |
http://purl.bioontology.org/ontology/MESH/D016723 |
| altLabel |
Turnover, Bone Bone Turnover Bone Turnovers Turnovers, Bone Remodeling, Bone |
| AN |
note category: an aspect of bone physiol |
| AQL |
DE GE IM PH RE |
| cui |
C0085268 |
| DC |
1 |
| definition |
The continuous turnover of BONE MATRIX and mineral that involves first an increase in BONE RESORPTION (osteoclastic activity) and later, reactive BONE FORMATION (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium HOMEOSTASIS. An imbalance in the regulation of bone remodeling's two contrasting events, bone resorption and bone formation, results in many of the metabolic bone diseases, such as OSTEOPOROSIS. |
| DX |
19920101 |
| HN |
92 |
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000528 http://purl.bioontology.org/ontology/MESH/Q000235 |
| Inverse of SIB |
http://purl.bioontology.org/ontology/MESH/D010809 http://purl.bioontology.org/ontology/MESH/D009119 http://purl.bioontology.org/ontology/MESH/D009129 http://purl.bioontology.org/ontology/MESH/D014945 http://purl.bioontology.org/ontology/MESH/D005082 http://purl.bioontology.org/ontology/MESH/D009068 http://purl.bioontology.org/ontology/MESH/D009416 http://purl.bioontology.org/ontology/MESH/D010807 http://purl.bioontology.org/ontology/MESH/D011597 http://purl.bioontology.org/ontology/MESH/D065586 http://purl.bioontology.org/ontology/MESH/D041641 http://purl.bioontology.org/ontology/MESH/D011187 http://purl.bioontology.org/ontology/MESH/D015519 http://purl.bioontology.org/ontology/MESH/D004856 http://purl.bioontology.org/ontology/MESH/D008115 http://purl.bioontology.org/ontology/MESH/D018763 |
| Machine permutation |
92 |
| MDA |
19910429 |
| MMR |
20160602 |
| MN |
G16.762.150 G11.427.213 |
| notation |
D016723 |
| prefLabel |
Bone Remodeling |
| TERMUI |
T000874154 T050113 |
| TH |
NLM (1992) NLM (2016) |
| tui |
T042 |
| subClassOf |