National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Keratinocyte

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C12589

ALT_DEFINITION

Epidermal cells which synthesize keratin and undergo characteristic changes as they move upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. Successive stages of differentiation of the keratinocytes forming the epidermal layers are basal cell, spinous or prickle cell, and the granular cell.

vertebrate, epidermal cell of ectodermal origin.

code

C12589

DEFINITION

The keratin-producing cells of the epidermis. They are the predominant cells of the epidermis that form in the deep basal layer of the stratified epithelium of the epidermis. They gradually migrate upward to the cornified layer of the epidermis undergoing characteristic changes.

Display_Name

Keratinocyte

FULL_SYN

Keratinocytes

label

Keratinocyte

Legacy_Concept_Name

Keratinocyte

Preferred_Name

Keratinocyte

prefixIRI

C12589

prefLabel

Keratinocyte

Semantic_Type

Cell

UMLS_CUI

C0022567

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C33562

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