National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Intermediate Filament

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C13248

ALT_DEFINITION

Cytoplasmic filaments intermediate in diameter (about 10 nanometers) between the microfilaments and the microtubules. They may be composed of any of a number of different proteins and form a ring around the cell nucleus.

code

C13248

DEFINITION

A class of tough protein filaments (including keratin filaments, neurofilaments, desmin, and vimentin) that measure 8-10 nm in thickness and comprise part of the cytoskeleton of the cytoplasm of most eukaryotic cells; so named because they are intermediate in thickness between actin filaments and microtubules.

label

Intermediate Filament

Legacy_Concept_Name

Intermediate_Filament

Preferred_Name

Intermediate Filament

prefixIRI

C13248

prefLabel

Intermediate Filament

Semantic_Type

Cell Component

UMLS_CUI

C0021770

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C32603

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http://purl.obolibrary.org/obo/GO_0005882 Human Phenotype Ontology China LOOM
http://purl.obolibrary.org/obo/GO_0005882 Cell Ontology LOOM
http://purl.obolibrary.org/obo/GO_0005882 Gene Ontology LOOM
http://purl.obolibrary.org/obo/FMA_63851 Foundational Model of Anatomy LOOM