National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Ribosome

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C13274

ALT_DEFINITION

In biology, a structure found inside cells that is involved in making proteins. Ribosomes help link amino acids together to form proteins.

code

C13274

DEFINITION

Ribosomes are small organelles composed of ribosomal RNA (rRNA) and 80 some different proteins. rRNA is synthesized in the nucleolus and the ribosomal subunits are assembled there from rRNA and imported cytoplasmic made proteins. Once assembled, the subunits pass through the nuclear pores to the cytoplasm where they take part in protein synthesis. Some ribosomes are free in the cytoplasm and can be recruited to a polyribosomal structure when a messenger RNA (mRNA) strand is to be translated into a cytoplasmic protein. Other ribosomes are attached to the endoplasmic reticulum where the protein is formed within the interior to the endoplasmic reticulum. These proteins are destined for secretion, storage or incorporation into membranes.

FULL_SYN

Ribosomal

label

Ribosome

Legacy_Concept_Name

Ribosome

Preferred_Name

Ribosome

prefixIRI

C13274

prefLabel

Ribosome

Semantic_Type

Cell Component

UMLS_CUI

C0035553

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C33174

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http://purl.obolibrary.org/obo/GO_0005840 Human Phenotype Ontology China LOOM
http://purl.obolibrary.org/obo/GO_0005840 Phenotypic Quality Ontology LOOM
http://purl.obolibrary.org/obo/GO_0005840 Cell Ontology LOOM
http://purl.obolibrary.org/obo/GO_0005840 Gene Ontology LOOM
http://purl.obolibrary.org/obo/FMA_66867 Foundational Model of Anatomy LOOM