National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Hemidesmosome

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C13327

ALT_DEFINITION

An anchoring junction of the cell to a non-cellular substrate, similar in morphology to halves of DESMOSOMES. They are composed of specialized areas of the plasma membrane where INTERMEDIATE FILAMENTS bind on the cytoplasmic face to the transmembrane linkers, INTEGRINS, via intracellular attachment proteins, while the extracellular domain of the integrins binds to EXTRACELLULAR MATRIX PROTEINS.

code

C13327

DEFINITION

Half desmosomes that occur on the basal surface of the stratum basalis of stratified squamous epithelium.

label

Hemidesmosome

Legacy_Concept_Name

Hemidesmosome

Preferred_Name

Hemidesmosome

prefixIRI

C13327

prefLabel

Hemidesmosome

Semantic_Type

Cell Component

UMLS_CUI

C0230616

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C13984

Delete Subject Author Type Created
No notes to display
Create New Mapping

Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/FMA_67415 Foundational Model of Anatomy LOOM
http://purl.obolibrary.org/obo/GO_0030056 Human Phenotype Ontology China LOOM
http://purl.obolibrary.org/obo/GO_0030056 Gene Ontology LOOM