National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Signal Transduction

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17133

ALT_DEFINITION

The process by which a cell responds to substances in its environment. The binding of a substance to a molecule on the surface of a cell causes signals to be passed from one molecule to another inside the cell. These signals can affect many functions of the cell, including cell division and cell death. Cells that have permanent changes in signal transduction molecules may develop into cancer.

code

C17133

DEFINITION

A cellular process that involves a chemical or mechanical stimulus and results in a specific cellular response. This process is a central feature of a broad variety of physiologic responses.

FULL_SYN

Cell Signaling

Cell Communication and Signaling

Intracellular Communication and Signaling

Signaling

label

Signal Transduction

Legacy_Concept_Name

Signal_Transduction

Preferred_Name

Signal Transduction

prefixIRI

C17133

prefLabel

Signal Transduction

Semantic_Type

Molecular Function

UMLS_CUI

C0037083

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20480

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http://purl.bioontology.org/ontology/MESH/D015398 Medical Subject Headings LOOM
http://purl.obolibrary.org/obo/GO_0007165 Human Phenotype Ontology China LOOM
http://purl.obolibrary.org/obo/GO_0007165 International Classification of Diseases Ontology LOOM
http://purl.obolibrary.org/obo/GO_0007165 Phenotypic Quality Ontology LOOM
http://purl.obolibrary.org/obo/GO_0007165 Cell Ontology LOOM
http://purl.obolibrary.org/obo/GO_0007165 Gene Ontology LOOM