National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Inflammatory Response

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20151

code

C20151

DEFINITION

A part of innate immunity, the Inflammatory Response occurs when injured tissues induce release of vasodilatory, opsonizing, and chemotactic mediators that attract macrophages and leukocytes to phagocytize and destroy foreign substances; dilate local blood vessels increasing local blood flow; increase capillary permeability; produce edematous swelling; and induce pain. Plasma- and cell-derived inflammatory mediators include Prostaglandins, Leukotrines, Cytokines, Lymphokines, Monokines, PAF, Histamine, Bradykinin, Complement, and Interferons.

FULL_SYN

Inflammation Process, Multicellular

Inflammation Process

label

Inflammatory Response

Legacy_Concept_Name

Inflammatory_Response

Preferred_Name

Inflammatory Response

prefixIRI

C20151

prefLabel

Inflammatory Response

Semantic_Type

Organ or Tissue Function

UMLS_CUI

C1155266

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18839

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http://purl.obolibrary.org/obo/GO_0006954 Human Phenotype Ontology China LOOM
http://purl.obolibrary.org/obo/GO_0006954 International Classification of Diseases Ontology LOOM
http://purl.obolibrary.org/obo/GO_0006954 Phenotypic Quality Ontology LOOM
http://purl.obolibrary.org/obo/GO_0006954 Cell Ontology LOOM
http://purl.obolibrary.org/obo/GO_0006954 Gene Ontology LOOM