National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Interleukin-3

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20439

ALT_DEFINITION

One of a group of related proteins made by leukocytes (white blood cells) and other cells in the body. IL-3 is made mainly by a type of T lymphocyte. It increases the number of blood cells made by the bone marrow. IL-3 made in the laboratory is used as a biological response modifier to boost the immune system in cancer therapy. IL-3 is a type of cytokine.

code

C20439

DEFINITION

Interleukin-3 (152 aa, ~17 kDa) is encoded by the human IL3 gene. This protein plays a role in neurotrophic activity and the proliferation of several types of hematopoietic lineage cells.

FULL_SYN

Erythrocyte Burst-Promoting Factor

IL-3

Mast-Cell Growth Factor

Mast Cell Growth Factor

P-Cell Stimulating Factor

Interleukin 3

P-Cell-Stimulating Factor

Colony-Stimulating Factor 2 Alpha

IL3

MULTI-CSF

IL3 Protein

MCGF

Multipotential Colony-Stimulating Factor

Eosinophil-Mast Cell Growth-Factor

Interleukin 3 Precursor

Multilineage-Colony-Stimulating Factor

Mast-Cell Colony-Stimulating Factor

label

Interleukin-3

Legacy_Concept_Name

Interleukin-3

OMIM_Number

147740

Preferred_Name

Interleukin-3

prefixIRI

C20439

prefLabel

Interleukin-3

Semantic_Type

Immunologic Factor

Amino Acid, Peptide, or Protein

Swiss_Prot

P08700

UMLS_CUI

C0021757

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20497

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20427

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http://purl.bioontology.org/ontology/MESH/D007377 Medical Subject Headings LOOM
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http://purl.obolibrary.org/obo/PR_000001387 Protein Ontology LOOM
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