National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Interleukin-13

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20515

ALT_DEFINITION

One of a group of related proteins made by leukocytes (white blood cells) and other cells in the body. IL-13 is made by a type of T lymphocyte. It reduces inflammation by blocking production of cytokines by macrophages. It also increases the number and activity of B lymphocytes. IL-13 made in the laboratory is used as a biological response modifier to boost the immune system in cancer therapy. It is a type of cytokine.

code

C20515

DEFINITION

Interleukin-13 (146 aa, ~16 kDa) is encoded by the human IL13 gene. This protein plays a role in the negative regulation of cytokine production and the positive regulation of B-cell proliferation.

FULL_SYN

Interleukin 13

IL-13

IL13

label

Interleukin-13

Legacy_Concept_Name

Interleukin-13

OMIM_Number

147683

Preferred_Name

Interleukin-13

prefixIRI

C20515

prefLabel

Interleukin-13

Semantic_Type

Immunologic Factor

Amino Acid, Peptide, or Protein

Swiss_Prot

P35225

UMLS_CUI

C0214743

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20497

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http://purl.obolibrary.org/obo/FMA_264824 Foundational Model of Anatomy LOOM
http://purl.bioontology.org/ontology/LNC/LP31544-7 Logical Observation Identifier Names and Codes LOOM
http://purl.obolibrary.org/obo/PR_000001370 Human Phenotype Ontology China LOOM
http://purl.obolibrary.org/obo/PR_000001370 Protein Ontology LOOM
http://purl.bioontology.org/ontology/LNC/MTHU015185 Logical Observation Identifier Names and Codes LOOM
http://purl.bioontology.org/ontology/MESH/D018793 Medical Subject Headings LOOM
http://purl.bioontology.org/ontology/OMIM/147683 Online Mendelian Inheritance in Man LOOM