National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Jump to:
Spinner 000000 16px loading...
Preferred Name

Complement Activation
ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C21519
code

C21519
DEFINITION

Any physiologic process in which a protease directs the cleavage of complement components C4, C2, or factor B which then form the C3 and C5 convertases for the classical and lectin pathways, respectively. This process is involved in direct lysis of target cells, immune adherence and phagocytosis of pathogens, and recruitment and activation of immunocompetent cells.
label

Complement Activation
Legacy_Concept_Name

Complement_Activation
Preferred_Name

Complement Activation
prefixIRI

C21519
prefLabel

Complement Activation
Semantic_Type

Molecular Function
UMLS_CUI

C0009528
subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17930
Add comment
Add proposal
Delete Subject Author Type Created
No notes to display
Create New Mapping

Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/GO_0006956 Human Phenotype Ontology China LOOM
http://purl.obolibrary.org/obo/GO_0006956 Gene Ontology LOOM
http://purl.bioontology.org/ontology/MESH/D003167 Medical Subject Headings LOOM