National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Antioxidant

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C275

ALT_DEFINITION

A substance that protects cells from the damage caused by free radicals (unstable molecules made by the process of oxidation during normal metabolism). Free radicals may play a part in cancer, heart disease, stroke, and other diseases of aging. Antioxidants include beta-carotene, lycopene, vitamins A, C, and E, and other natural and manufactured substances.

CHEBI_ID

CHEBI:22586

code

C275

DEFINITION

A group of organic or inorganic substances capable of preventing the genotoxic and carcinogenic effects of free-radical compounds. Antioxidants bind to and neutralize ('scavenge') free radicals, thereby transforming them into non-toxic compounds and blocking their genotoxic and carcinogenic effects. This class of agents includes the vitamins C and E, the carotenoids, and selenium. Organic antioxidants are found in high concentrations in fruits, seeds and vegetables. (NCI04)

label

Antioxidant

Legacy_Concept_Name

Antioxidant

Preferred_Name

Antioxidant

prefixIRI

C275

prefLabel

Antioxidant

Semantic_Type

Chemical Viewed Functionally

UMLS_CUI

C0003402

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26170

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http://purl.obolibrary.org/obo/CHEBI_22586 Chemical Entities of Biological Interest Ontology LOOM
http://purl.obolibrary.org/obo/CHEBI_22586 Human Phenotype Ontology China LOOM
http://purl.obolibrary.org/obo/CHEBI_22586 International Classification of Diseases Ontology LOOM
http://purl.obolibrary.org/obo/CHEBI_22586 Cell Ontology LOOM