National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Ascorbic Acid

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C285

Accepted_Therapeutic_Use_For

Ascorbic acid deficiency; Burns; Iron nutrition; Scurvy; Wound healing

ALT_DEFINITION

The functional and primary form of vitamin C; it is the enolic form of an alpha-ketolactone.

A nutrient that the body needs in small amounts to function and stay healthy. Ascorbic acid helps fight infections, heal wounds, and keep tissues healthy. It is an antioxidant that helps prevent cell damage caused by free radicals (highly reactive chemicals). Ascorbic acid is found in all fruits and vegetables, especially citrus fruits, strawberries, cantaloupe, green peppers, tomatoes, broccoli, leafy greens, and potatoes. It is water-soluble (can dissolve in water) and must be taken in every day. Ascorbic acid is being studied in the prevention and treatment of some types of cancer.

CAS_Registry

50-81-7

CHEBI_ID

CHEBI:29073

Chemical_Formula

C6H8O6

code

C285

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978

Contributing_Source

CTRP

CRCH

FDA

DEFINITION

A natural water-soluble vitamin (Vitamin C). Ascorbic acid is a potent reducing and antioxidant agent that functions in fighting bacterial infections, in detoxifying reactions, and in the formation of collagen in fibrous tissue, teeth, bones, connective tissue, skin, and capillaries. Found in citrus and other fruits, and in vegetables, vitamin C cannot be produced or stored by humans and must be obtained in the diet. (NCI04)

Display_Name

Ascorbic Acid

FDA_UNII_Code

PQ6CK8PD0R

FULL_SYN

Vitamin-C

C Vitamin

C-Long

Ce-Vi-Sol

L-Ascorbic Acid

Cecon

2-(1,2-dihydroxyethyl)-4,5-dihydroxy-furan-3-one

Cevalin

Cetane

Vitamin C

VIT C

Cenolate

Asorbicap

label

Ascorbic Acid

Legacy_Concept_Name

Ascorbic_Acid

NSC_Code

33832

PDQ_Closed_Trial_Search_ID

39737

PDQ_Open_Trial_Search_ID

39737

Preferred_Name

Ascorbic Acid

prefixIRI

C285

prefLabel

Ascorbic Acid

Semantic_Type

Organic Chemical

Pharmacologic Substance

Vitamin

UMLS_CUI

C0003968

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C68507

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C275

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http://purl.bioontology.org/ontology/MEDLINEPLUS/C0003968 MedlinePlus Health Topics LOOM
http://purl.bioontology.org/ontology/MESH/D001205 Medical Subject Headings LOOM
http://purl.obolibrary.org/obo/CHEBI_22652 Chemical Entities of Biological Interest Ontology LOOM
http://purl.obolibrary.org/obo/CHEBI_22652 Human Phenotype Ontology China LOOM