| Preferred Name |
Rheumatoid Arthritis |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2884 |
| ALT_DEFINITION |
An autoimmune disease that causes pain, swelling, and stiffness in the joints, and may cause severe joint damage, loss of function, and disability. The disease may last from months to a lifetime, and symptoms may improve and worsen over time. A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated. A chronic, inflammatory condition manifesting primarily as a symmetric, erosive, polyarthritis that spares the axial skeleton and is typically associated with rheumatoid factor and anti-citrullinated protein antibodies. |
| code |
C2884 |
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118468 |
| Contributing_Source |
NICHD FDA |
| DEFINITION |
A chronic, systemic autoimmune disorder characterized by inflammation in the synovial membranes and articular surfaces. It manifests primarily as a symmetric, erosive polyarthritis that spares the axial skeleton and is typically associated with the presence in the serum of rheumatoid factor. |
| FDA_Table |
Patient Code (Appendix B) |
| FULL_SYN |
Arthritis, Rheumatoid RA |
| Has_CDRH_Parent | |
| Has_NICHD_Parent | |
| label |
Rheumatoid Arthritis |
| Legacy_Concept_Name |
Rheumatoid_Arthritis |
| NICHD_Hierarchy_Term |
Rheumatoid Arthritis |
| Preferred_Name |
Rheumatoid Arthritis |
| prefixIRI |
C2884 |
| prefLabel |
Rheumatoid Arthritis |
| Semantic_Type |
Disease or Syndrome |
| UMLS_CUI |
C0003873 |
| subClassOf |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C27204 |