National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Rheumatoid Arthritis

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2884

ALT_DEFINITION

An autoimmune disease that causes pain, swelling, and stiffness in the joints, and may cause severe joint damage, loss of function, and disability. The disease may last from months to a lifetime, and symptoms may improve and worsen over time.

A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.

A chronic, inflammatory condition manifesting primarily as a symmetric, erosive, polyarthritis that spares the axial skeleton and is typically associated with rheumatoid factor and anti-citrullinated protein antibodies.

code

C2884

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118468

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90259

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C54450

Contributing_Source

NICHD

FDA

DEFINITION

A chronic, systemic autoimmune disorder characterized by inflammation in the synovial membranes and articular surfaces. It manifests primarily as a symmetric, erosive polyarthritis that spares the axial skeleton and is typically associated with the presence in the serum of rheumatoid factor.

FDA_Table

Patient Code (Appendix B)

FULL_SYN

Arthritis, Rheumatoid

RA

Has_CDRH_Parent

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2883

Has_NICHD_Parent

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2883

label

Rheumatoid Arthritis

Legacy_Concept_Name

Rheumatoid_Arthritis

NICHD_Hierarchy_Term

Rheumatoid Arthritis

Preferred_Name

Rheumatoid Arthritis

prefixIRI

C2884

prefLabel

Rheumatoid Arthritis

Semantic_Type

Disease or Syndrome

UMLS_CUI

C0003873

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C27204

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2883

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2889

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