National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Inflammation

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3137

ALT_DEFINITION

A response to an injury or abnormal stimuli characterized by inflammatory cell infiltration and varying degrees of vascular and tissue reactions (hyperemia, edema, fibrin, and/or fibrosis).

Redness, swelling, pain, and/or a feeling of heat in an area of the body. This is a protective reaction to injury, disease, or irritation of the tissues.

code

C3137

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61410

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C120531

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C54450

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C77526

Contributing_Source

CDISC

FDA

DEFINITION

A localized protective response resulting from injury or destruction of tissues. Inflammation serves to destroy, dilute, or wall off both the injurious agent and the injured tissue. In the acute phase, inflammation is characterized by the signs of pain, heat, redness, swelling, and loss of function. Histologically, inflammation involves a complex series of events, including dilatation of arterioles, capillaries, and venules, with increased permeability and blood flow; exudation of fluids, including plasma proteins; and leukocyte migration into the site of inflammation.

FDA_Table

Patient Code (Appendix B)

Has_CDRH_Parent

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C54027

label

Inflammation

Legacy_Concept_Name

Inflammation

Preferred_Name

Inflammation

prefixIRI

C3137

prefLabel

Inflammation

Semantic_Type

Finding

UMLS_CUI

C0021368

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C36295

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http://purl.obolibrary.org/obo/MPATH_212 Human Phenotype Ontology China LOOM
http://purl.bioontology.org/ontology/MESH/D007249 Medical Subject Headings LOOM
http://purl.obolibrary.org/obo/SYMP_0000061 Human Disease Ontology 123 LOOM
http://www.semanticweb.org/tome/ontologies/2015/7/Richfields#Inflammation A formal representation of the knowledge within the domain of Isotopes for Food Science LOOM
http://purl.bioontology.org/ontology/OMIM/MTHU010576 Online Mendelian Inheritance in Man LOOM
http://purl.bioontology.org/ontology/LNC/LA7447-1 Logical Observation Identifier Names and Codes LOOM