National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Retinol

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C68302

ALT_DEFINITION

Retinoid with a hydroxyl group. Active form of vitamin A which can be converted to the other usable forms; retinal (an aldehyde) and retinoic acid (a carboxylic acid).

CAS_Registry

68-26-8

11103-57-4

CHEBI_ID

CHEBI:17336

Chemical_Formula

C20H30O

code

C68302

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

CRCH

FDA

DEFINITION

The fat soluble vitamin retinol. Vitamin A binds to and activates retinoid receptors (RARs), thereby inducing cell differentiation and apoptosis of some cancer cell types and inhibiting carcinogenesis. Vitamin A plays an essential role in many physiologic processes, including proper functioning of the retina, growth and differentiation of target tissues, proper functioning of the reproductive organs, and modulation of immune function.

FDA_UNII_Code

G2SH0XKK91

FULL_SYN

3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol

All Trans Retinol

3,7-Dimethyl-9-(2,6, 6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol

3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)-nona-2,4,6,8-tetraen-1-ol

INFOODS

RETOL

label

Retinol

Legacy_Concept_Name

Retinol

PDQ_Closed_Trial_Search_ID

39735

PDQ_Open_Trial_Search_ID

39735

Preferred_Name

Retinol

prefixIRI

C68302

prefLabel

Retinol

Semantic_Type

Vitamin

UMLS_CUI

C0087161

Unit

mcg

USDA_ID

322

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C68299

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C938

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http://purl.bioontology.org/ontology/LNC/LP15274-1 Logical Observation Identifier Names and Codes LOOM
http://purl.obolibrary.org/obo/CHEBI_50211 Chemical Entities of Biological Interest Ontology LOOM
http://purl.obolibrary.org/obo/CHEBI_50211 Human Phenotype Ontology China LOOM
http://purl.obolibrary.org/obo/CHEBI_50211 GenEpiO LOOM
http://purl.bioontology.org/ontology/LNC/MTHU005041 Logical Observation Identifier Names and Codes LOOM
http://purl.bioontology.org/ontology/MEDLINEPLUS/C0087161 MedlinePlus Health Topics LOOM