Nicotine

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C691

Smoking Cessation

An addictive, poisonous chemical found in tobacco. It can also be made in the laboratory. When it enters the body, nicotine causes an increased heart rate and use of oxygen by the heart, and a sense of well-being and relaxation. It is also used as an insecticide.

Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.

54-11-5

CHEBI:17688

C10H14N2

C691

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978

CTRP

FDA

A plant alkaloid, found in the tobacco plant, and addictive central nervous system (CNS) stimulant that causes either ganglionic stimulation in low doses or ganglionic blockage in high doses. Nicotine acts as an agonist at the nicotinic cholinergic receptors in the autonomic ganglia, at neuromuscular junctions, and in the adrenal medulla and the brain. Nicotine's CNS-stimulating activities may be mediated through the release of several neurotransmitters, including acetylcholine, beta-endorphin, dopamine, norepinephrine, serotonin, and ACTH. As a result, peripheral vasoconstriction, tachycardia, and elevated blood pressure may be observed with nicotine intake. This agent may also stimulate the chemoreceptor trigger zone, thereby inducing nausea and vomiting.

Nicotine

6M3C89ZY6R

NIC

(S)-3-(1-Methyl-2-pyrrolidinyl)pyridine

(-)-Nicotine

beta-Pyridyl-alpha-N-methylpyrrolidine

1-Methyl-2-(3-pyridyl)pyrrolidine

Nicotine

Nicotine

5065

42243

42243

Nicotine

C691

Nicotine

Organic Chemical

Pharmacologic Substance

C0028040

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C221

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C73579