National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Purine

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C786

ALT_DEFINITION

One of two chemical compounds that cells use to make the building blocks of DNA and RNA. Examples of purines are adenine and guanine. Purines are also found in meat and meat products. They are broken down by the body to form uric acid, which is passed in the urine. High levels of uric acid in the body may cause gout.

A series of heterocyclic compounds that are variously substituted in nature and are known also as purine bases. They include ADENINE and GUANINE, constituents of nucleic acids, as well as many alkaloids such as CAFFEINE and THEOPHYLLINE. Uric acid is the metabolic end product of purine metabolism.

bicyclic ring structure consisting of fused imidazole and pyrimidine rings, with nitrogen atoms at the 1,3,7, and 9 positions; the basic structure of adenine, guanine, and other biologically important bases.

CAS_Registry

120-73-0

CHEBI_ID

CHEBI:35584

CHEBI:35586

CHEBI:35589

CHEBI:17258

Chemical_Formula

C5H4N4

code

C786

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

FDA_UNII_Code

W60KTZ3IZY

FULL_SYN

beta-Purine

1H-Purine

label

Purine

Legacy_Concept_Name

Purine

NSC_Code

753

Preferred_Name

Purine

prefixIRI

C786

prefLabel

Purine

Semantic_Type

Organic Chemical

UMLS_CUI

C0034140

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C542

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http://purl.obolibrary.org/obo/FMA_82772 Foundational Model of Anatomy LOOM
http://purl.bioontology.org/ontology/LNC/LP247699-4 Logical Observation Identifier Names and Codes LOOM
http://purl.obolibrary.org/obo/CHEBI_35584 Chemical Entities of Biological Interest Ontology LOOM
http://purl.obolibrary.org/obo/CHEBI_35584 Human Phenotype Ontology China LOOM
http://purl.obolibrary.org/obo/CHEBI_35584 International Classification of Diseases Ontology LOOM
http://purl.bioontology.org/ontology/MESH/C030985 Medical Subject Headings LOOM