National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Gamma-Aminobutyric Acid

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C80523

CAS_Registry

56-12-2

CHEBI_ID

CHEBI:16865

Chemical_Formula

C4H9NO2

code

C80523

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A naturally occurring neurotransmitter with central nervous system (CNS) inhibitory activity. Gamma-aminobutyric acid (GABA), converted from the principal excitatory neurotransmitter glutamate in the brain, plays a role in regulating neuronal excitability by binding to its receptors, GABA-A and GABA-B, and thereby causing ion channel opening, hyperpolarization and eventually inhibition of neurotransmission.

FDA_UNII_Code

2ACZ6IPC6I

FULL_SYN

.GAMMA.-AMINOBUTYRIC ACID

GABA

Piperidic Acid

4-Aminobutanoic Acid

label

Gamma-Aminobutyric Acid

Legacy_Concept_Name

Gamma-Aminobutyric_Acid

Preferred_Name

Gamma-Aminobutyric Acid

prefixIRI

C80523

prefLabel

Gamma-Aminobutyric Acid

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0016904

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C687

Delete Subject Author Type Created
No notes to display
Create New Mapping

Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_16865 Chemical Entities of Biological Interest Ontology LOOM
http://purl.obolibrary.org/obo/CHEBI_16865 Human Phenotype Ontology China LOOM
http://purl.obolibrary.org/obo/CHEBI_16865 Cell Ontology LOOM
http://purl.bioontology.org/ontology/MESH/D005680 Medical Subject Headings LOOM
http://purl.obolibrary.org/obo/FMA_84786 Foundational Model of Anatomy LOOM