Preferred Name |
Malignant Neoplasm |
ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C9305 |
ALT_DEFINITION |
Uncontrolled growth of abnormal cells with potential for metastatic spread. A term for diseases in which abnormal cells divide without control and can invade nearby tissues. Malignant cells can also spread to other parts of the body through the blood and lymph systems. There are several main types of malignancy. Carcinoma is a malignancy that begins in the skin or in tissues that line or cover internal organs. Sarcoma is a malignancy that begins in bone, cartilage, fat, muscle, blood vessels, or other connective or supportive tissue. Leukemia is a malignancy that starts in blood-forming tissue such as the bone marrow, and causes large numbers of abnormal blood cells to be produced and enter the blood. Lymphoma and multiple myeloma are malignancies that begin in the cells of the immune system. Central nervous system cancers are malignancies that begin in the tissues of the brain and spinal cord. A general term for autonomous tissue growth exhibiting morphologic features of malignancy (e.g. severe atypia, nuclear pleomorphism, tumor cell necrosis, abnormal mitoses, tissue invasiveness) and for which the transformed cell type has not been specifically identified. |
code |
C9305 |
Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C19752 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66830 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C88025 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61410 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118464 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90259 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C54450 |
Contributing_Source |
CTRP CDISC NICHD MedDRA FDA |
DEFINITION |
A tumor composed of atypical neoplastic, often pleomorphic cells that invade other tissues. Malignant neoplasms often metastasize to distant anatomic sites and may recur after excision. The most common malignant neoplasms are carcinomas (adenocarcinomas or squamous cell carcinomas), Hodgkin and non-Hodgkin lymphomas, leukemias, melanomas, and sarcomas. |
Display_Name |
Malignant Neoplasm |
FULL_SYN |
Malignant Growth Malignant Neoplastic Disease Malignant Tumor NEOPLASM, MALIGNANT CA Cancer Malignancy |
Has_CDRH_Parent | |
Has_NICHD_Parent | |
ICD-O-3_Code |
8000/3 |
label |
Malignant Neoplasm |
Legacy_Concept_Name |
Malignant_Neoplasm |
Neoplastic_Status |
Malignant |
NICHD_Hierarchy_Term |
Cancer |
Preferred_Name |
Malignant Neoplasm |
prefixIRI |
C9305 |
prefLabel |
Malignant Neoplasm |
Semantic_Type |
Neoplastic Process |
UMLS_CUI |
C0006826 |
subClassOf |
Delete | Mapping To | Ontology | Source |
---|---|---|---|
http://purl.obolibrary.org/obo/NCIT_C9305 | Human Phenotype Ontology China | LOOM |