National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Malignant Neoplasm

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C9305

ALT_DEFINITION

Uncontrolled growth of abnormal cells with potential for metastatic spread.

A term for diseases in which abnormal cells divide without control and can invade nearby tissues. Malignant cells can also spread to other parts of the body through the blood and lymph systems. There are several main types of malignancy. Carcinoma is a malignancy that begins in the skin or in tissues that line or cover internal organs. Sarcoma is a malignancy that begins in bone, cartilage, fat, muscle, blood vessels, or other connective or supportive tissue. Leukemia is a malignancy that starts in blood-forming tissue such as the bone marrow, and causes large numbers of abnormal blood cells to be produced and enter the blood. Lymphoma and multiple myeloma are malignancies that begin in the cells of the immune system. Central nervous system cancers are malignancies that begin in the tissues of the brain and spinal cord.

A general term for autonomous tissue growth exhibiting morphologic features of malignancy (e.g. severe atypia, nuclear pleomorphism, tumor cell necrosis, abnormal mitoses, tissue invasiveness) and for which the transformed cell type has not been specifically identified.

code

C9305

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C19752

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66830

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C88025

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61410

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118464

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90259

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C54450

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C99147

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C77526

Contributing_Source

CTRP

CDISC

NICHD

MedDRA

FDA

DEFINITION

A tumor composed of atypical neoplastic, often pleomorphic cells that invade other tissues. Malignant neoplasms often metastasize to distant anatomic sites and may recur after excision. The most common malignant neoplasms are carcinomas (adenocarcinomas or squamous cell carcinomas), Hodgkin and non-Hodgkin lymphomas, leukemias, melanomas, and sarcomas.

Display_Name

Malignant Neoplasm

FULL_SYN

Malignant Growth

Malignant Neoplastic Disease

Malignant Tumor

NEOPLASM, MALIGNANT

CA

Cancer

Malignancy

Has_CDRH_Parent

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C54027

Has_NICHD_Parent

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3262

ICD-O-3_Code

8000/3

label

Malignant Neoplasm

Legacy_Concept_Name

Malignant_Neoplasm

Neoplastic_Status

Malignant

NICHD_Hierarchy_Term

Cancer

Preferred_Name

Malignant Neoplasm

prefixIRI

C9305

prefLabel

Malignant Neoplasm

Semantic_Type

Neoplastic Process

UMLS_CUI

C0006826

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7062

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http://purl.obolibrary.org/obo/NCIT_C9305 Human Phenotype Ontology China LOOM