loading...| Preferred Name |
Lactotransferrin |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C94665 |
| ALT_DEFINITION |
A protein that is found in milk, tears, mucus, bile, and some white blood cells and is being studied in the treatment and prevention of cancer. It is involved in fighting against infection and inflammation and it acts as an antioxidant. |
| code |
C94665 |
| DEFINITION |
Lactotransferrin (710 aa, ~78 kDa) is encoded by the human LTF gene. This protein is involved in the mediation of both proteolysis and iron transport. |
| DesignNote |
The lactotransferrin transferrin-like domain 1 can act as a serine protease of the peptidase S60 family that cuts arginine rich regions. This enzymatic function contributes to the antimicrobial activity. (UniProt) Lactotransferrin can be cleaved to form lactoferricin-H (Lfcin-H), kaliocin-1, lactoferroxin-A, lactoferroxin-B and, lactoferroxin-C. Lactoferroxins A, B and C have opioid antagonist activity. (UniProt) |
| FULL_SYN |
Neutrophil Lactoferrin EC 3.4.21.- Talalactoferrin Growth-Inhibiting Protein 12 Lactoferrin Epididymis Luminal Protein 110 |
| label |
Lactotransferrin |
| OMIM_Number |
150210 |
| Preferred_Name |
Lactotransferrin |
| prefixIRI |
C94665 |
| prefLabel |
Lactotransferrin |
| Semantic_Type |
Amino Acid, Peptide, or Protein |
| Swiss_Prot |
Q8TCD2 |
| UMLS_CUI |
C0022942 |
| subClassOf |