Cell Ontology

Last uploaded: February 23, 2022
Preferred Name

follicular dendritic cell

Definitions

Due to its unique lineage and distinct function, this is not a type of dendritic cell; CL:0000451. A cell with extensive dendritic processes found in the B cell areas (primary follicles and germinal centers) of lymphoid tissue. They are unrelated to the dendritic cell associated with T cells. Follicular dendritic cells have Fc receptors and C3b receptors, but unlike other dendritic cells, they do not process or present antigen in a way that allows recognition by T cells. Instead, they hold antigen in the form of immune complexes on their surfaces for long periods and can present antigen to B cells during an immune response.

ID

http://purl.obolibrary.org/obo/CL_0000442

comment

Due to its unique lineage and distinct function, this is not a type of dendritic cell; CL:0000451.

database_cross_reference

BTO:0004267

FMA:83037

definition

A cell with extensive dendritic processes found in the B cell areas (primary follicles and germinal centers) of lymphoid tissue. They are unrelated to the dendritic cell associated with T cells. Follicular dendritic cells have Fc receptors and C3b receptors, but unlike other dendritic cells, they do not process or present antigen in a way that allows recognition by T cells. Instead, they hold antigen in the form of immune complexes on their surfaces for long periods and can present antigen to B cells during an immune response.

has_obo_namespace

cell

label

follicular dendritic cell

prefixIRI

CL:0000442

prefLabel

follicular dendritic cell

subClassOf

http://purl.obolibrary.org/obo/CL_0000473

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http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C12622 National Cancer Institute Thesaurus LOOM
http://purl.obolibrary.org/obo/BTO_0004267 BRENDA Tissue and Enzyme Source Ontology LOOM
http://purl.obolibrary.org/obo/FMA_83037 Foundational Model of Anatomy LOOM
http://purl.obolibrary.org/obo/CL_0000442 Human Phenotype Ontology China LOOM
http://purl.obolibrary.org/obo/CL_0000442 Human Phenotype Ontology China SAME_URI
http://purl.obolibrary.org/obo/CL_0000442 Human Disease Ontology 123 LOOM
http://purl.obolibrary.org/obo/CL_0000442 Human Disease Ontology 123 SAME_URI