Gene Ontology

Last uploaded: February 21, 2019
Preferred Name

nuclear lamina

Definitions

The fibrous, electron-dense layer lying on the nucleoplasmic side of the inner membrane of a cell nucleus, composed of lamin filaments. The polypeptides of the lamina are thought to be concerned in the dissolution of the nuclear envelope and its re-formation during mitosis. The lamina is composed of lamin A and lamin C filaments cross-linked into an orthogonal lattice, which is attached via lamin B to the inner nuclear membrane through interactions with a lamin B receptor, an IFAP, in the membrane.

ID

http://purl.obolibrary.org/obo/GO_0005652

database_cross_reference

Wikipedia:Nuclear_lamina

NIF_Subcellular:sao1455996588

definition

The fibrous, electron-dense layer lying on the nucleoplasmic side of the inner membrane of a cell nucleus, composed of lamin filaments. The polypeptides of the lamina are thought to be concerned in the dissolution of the nuclear envelope and its re-formation during mitosis. The lamina is composed of lamin A and lamin C filaments cross-linked into an orthogonal lattice, which is attached via lamin B to the inner nuclear membrane through interactions with a lamin B receptor, an IFAP, in the membrane.

has_obo_namespace

cellular_component

id

GO:0005652

label

nuclear lamina

notation

GO:0005652

part_of

http://purl.obolibrary.org/obo/GO_0034399

prefLabel

nuclear lamina

treeView

http://purl.obolibrary.org/obo/GO_0034399

http://purl.obolibrary.org/obo/GO_0044428

subClassOf

http://purl.obolibrary.org/obo/GO_0044428

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http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C13809 National Cancer Institute Thesaurus LOOM
http://purl.obolibrary.org/obo/FMA_66852 Foundational Model of Anatomy LOOM
http://purl.obolibrary.org/obo/GO_0005652 Human Phenotype Ontology China LOOM
http://purl.obolibrary.org/obo/GO_0005652 Human Phenotype Ontology China SAME_URI
http://purl.bioontology.org/ontology/MESH/D034881 Medical Subject Headings LOOM