loading...| Preferred Name |
Erythrocyte Aggregation |
| Synonyms |
Erythrocyte Rouleaux Formation |
| Definitions |
The formation of clumps of RED BLOOD CELLS under low or non-flow conditions, resulting from the attraction forces between the red blood cells. The cells adhere to each other in rouleaux aggregates. Slight mechanical force, such as occurs in the circulation, is enough to disperse these aggregates. Stronger or weaker than normal aggregation may result from a variety of effects in the ERYTHROCYTE MEMBRANE or in BLOOD PLASMA. The degree of aggregation is affected by ERYTHROCYTE DEFORMABILITY, erythrocyte membrane sialylation, masking of negative surface charge by plasma proteins, etc. BLOOD VISCOSITY and the ERYTHROCYTE SEDIMENTATION RATE are affected by the amount of erythrocyte aggregation and are parameters used to measure the aggregation. |
| ID |
http://purl.bioontology.org/ontology/MESH/D004903 |
| altLabel |
Erythrocyte Rouleaux Formation Agglutinations, Intravascular Erythrocyte Aggregations, Intravascular Formations, Erythrocyte Rouleaux Aggregations, Erythrocyte Erythrocyte Aggregation, Intravascular Erythrocyte Rouleaux Formations Rouleaux Formation, Erythrocyte Intravascular Agglutinations Aggregation, Intravascular Erythrocyte Aggregation, Erythrocyte Intravascular Erythrocyte Aggregations Intravascular Agglutination Agglutination, Intravascular Erythrocyte Aggregations Formation, Erythrocyte Rouleaux Rouleaux Formations, Erythrocyte Aggregations, Intravascular Erythrocyte Intravascular Erythrocyte Aggregation |
| AN |
coord with disease /blood, not disease /physiopathol; do not confuse with DISSEMINATED INTRAVASCULAR COAGULATION; DF: ERYTHROCYTE AGGREGATION INTRAVASC |
| AQL |
DE ES GE IM PH RE |
| cui |
C1258012 C1258013 C0014767 C0014766 |
| DC |
1 |
| definition |
The formation of clumps of RED BLOOD CELLS under low or non-flow conditions, resulting from the attraction forces between the red blood cells. The cells adhere to each other in rouleaux aggregates. Slight mechanical force, such as occurs in the circulation, is enough to disperse these aggregates. Stronger or weaker than normal aggregation may result from a variety of effects in the ERYTHROCYTE MEMBRANE or in BLOOD PLASMA. The degree of aggregation is affected by ERYTHROCYTE DEFORMABILITY, erythrocyte membrane sialylation, masking of negative surface charge by plasma proteins, etc. BLOOD VISCOSITY and the ERYTHROCYTE SEDIMENTATION RATE are affected by the amount of erythrocyte aggregation and are parameters used to measure the aggregation. Aggregation of ERYTHROCYTES in vivo, caused by specific interactions such as those induced by antibodies. Clumping of ERYTHROCYTES, in vivo, in intact blood vessels. Increased and/or abnormal aggregation may lead to impairment of MICROCIRCULATION (blood sludging and THROMBUS formation) and development of VASCULAR DISEASES. The clumping of ERYTHROCYTES that is like a stack or roll of coins. |
| DX |
19760101 |
| FX |
D018056 |
| HN |
1976 |
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000941 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000528 http://purl.bioontology.org/ontology/MESH/Q000235 |
| Inverse of RO | |
| Inverse of SIB |
http://purl.bioontology.org/ontology/MESH/D001809 http://purl.bioontology.org/ontology/MESH/D001856 http://purl.bioontology.org/ontology/MESH/D006400 http://purl.bioontology.org/ontology/MESH/D001799 http://purl.bioontology.org/ontology/MESH/D010974 http://purl.bioontology.org/ontology/MESH/D005365 http://purl.bioontology.org/ontology/MESH/D004907 http://purl.bioontology.org/ontology/MESH/D001788 http://purl.bioontology.org/ontology/MESH/D010979 http://purl.bioontology.org/ontology/MESH/D009996 http://purl.bioontology.org/ontology/MESH/D012546 http://purl.bioontology.org/ontology/MESH/D001780 http://purl.bioontology.org/ontology/MESH/D004909 http://purl.bioontology.org/ontology/MESH/D001772 |
| Machine permutation |
1976; for ERYTHROCYTE AGGREGATION, INTRAVASCULAR see ERYTHROCYTE AGGREGATION, INTRAVASCULAR 1964-2003; for INTRAVASCULAR AGGLUTINATION see ERYTHROCYTE AGGREGATION, INTRAVASCULAR 1976-2003 |
| MDA |
19750725 |
| MMR |
20160617 |
| MN |
E01.370.225.625.225 E05.200.625.225 G09.188.370.187 |
| notation |
D004903 |
| prefLabel |
Erythrocyte Aggregation |
| TERMUI |
T014980 T014981 T537879 T014979 T014977 T014978 |
| TH |
NLM (2004) UNK (19XX) NLM (1992) NLM (1964) NLM (1976) |
| tui |
T043 T059 T047 |
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.obolibrary.org/obo/GO_0034117 | Human Phenotype Ontology China | LOOM | |
| http://purl.obolibrary.org/obo/GO_0034117 | Gene Ontology | LOOM |