loading...| Preferred Name |
RNA Interference |
| Synonyms |
Posttranscriptional Gene Silencing |
| Definitions |
Joint gene silencing of extra copies of genes, such as TRANSGENES, along with the original endogenous gene. Cosuppression is induced by the presence of the extra gene copies via mechanisms that are related to RNA INTERFERENCE. |
| ID |
http://purl.bioontology.org/ontology/MESH/D034622 |
| altLabel |
Posttranscriptional Gene Silencing Silencing, Post-Transcriptional Gene Gene Silencing, Post-Transcriptional RNA Silencing Gene Silencings, Posttranscriptional Post Transcriptional Gene Silencing Post-Transcriptional Gene Silencings Gene Silencing, Posttranscriptional Co Suppression Interference, RNA Post-Transcriptional Gene Silencing Gene Silencing, Post Transcriptional RNAi Cosuppression Co-Suppression |
| AQL |
DE IM PH RE |
| cui |
C1136031 C1956351 |
| DC |
1 |
| definition |
Joint gene silencing of extra copies of genes, such as TRANSGENES, along with the original endogenous gene. Cosuppression is induced by the presence of the extra gene copies via mechanisms that are related to RNA INTERFERENCE. A gene silencing phenomenon whereby specific dsRNAs (RNA, DOUBLE-STRANDED) trigger the degradation of homologous mRNA (RNA, MESSENGER). The specific dsRNAs are processed into SMALL INTERFERING RNA (siRNA) which serves as a guide for cleavage of the homologous mRNA in the RNA-INDUCED SILENCING COMPLEX. DNA METHYLATION may also be triggered during this process. |
| DX |
20030101 |
| FX |
D034741 D034743 D000067492 |
| HN |
2003 |
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000528 |
| Inverse of RO |
http://purl.bioontology.org/ontology/MESH/D000070416 http://purl.bioontology.org/ontology/MESH/D034743 |
| Inverse of SIB | |
| Machine permutation |
2003 |
| MDA |
20020703 |
| MMR |
20160617 |
| MN |
G05.308.203.374.790 |
| notation |
D034622 |
| prefLabel |
RNA Interference |
| TERMUI |
T471584 T695254 T471540 T471539 T471542 T695255 T000870922 T471541 |
| TH |
NLM (2008) NLM (2016) NLM (2003) |
| tui |
T070 T045 |
| subClassOf |