loading...| Preferred Name |
Gene Silencing by miRNA |
| Definitions |
Downregulation of gene expression through the action of microRNAs (miRNAs), endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: mRNA cleavage or translational repression. |
| ID |
http://purl.org/obo/owl/GO#GO_0035195 |
| definition |
Downregulation of gene expression through the action of microRNAs (miRNAs), endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: mRNA cleavage or translational repression. |
| definition_source |
GO:0035195 |
| has_agent | |
| label |
Gene Silencing by miRNA |
| prefixIRI |
GO:GO_0035195 |
| prefLabel |
Gene Silencing by miRNA |
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.obolibrary.org/obo/GO_0035195 | Human Phenotype Ontology China | LOOM | |
| http://purl.obolibrary.org/obo/GO_0035195 | Gene Ontology | LOOM |