National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Mismatch Repair

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20639

code

C20639

DEFINITION

The mismatch repair (MMR) system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination. This function is critically dependent on the assembly of multimeric complexes involved in mismatch recognition and signal transduction to downstream repair events.

FULL_SYN

MMR

DNA Mismatch Repair

Post-Replication Mismatch Repair

label

Mismatch Repair

Legacy_Concept_Name

Mismatch_Repair

Preferred_Name

Mismatch Repair

prefixIRI

C20639

prefLabel

Mismatch Repair

Semantic_Type

Genetic Function

UMLS_CUI

C1155661

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16513

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http://purl.obolibrary.org/obo/GO_0006298 Human Phenotype Ontology China LOOM
http://purl.obolibrary.org/obo/GO_0006298 Gene Ontology LOOM