National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Negative Regulation of Lymphocyte Activation

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C40846

code

C40846

DEFINITION

Lymphocyte Suppression involves interference with, or restraint of, the production and activity of lymphocytes. Formed in lymphoid tissue, lymphocytes are white blood cells that can generally be classified as either T- or B-cells. T-lymphocytes provide cell-mediated immunity, while B-lymphocytes produce antibodies that provide humoral immunity. Suppression decreases the ability of lymphocytes to mount an immune response to invading substances.

FULL_SYN

Lymphocyte Suppression

label

Negative Regulation of Lymphocyte Activation

Legacy_Concept_Name

Lymphocyte_Suppression

Preferred_Name

Negative Regulation of Lymphocyte Activation

prefixIRI

C40846

prefLabel

Negative Regulation of Lymphocyte Activation

Semantic_Type

Physiologic Function

UMLS_CUI

C1518065

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C40833

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http://purl.obolibrary.org/obo/GO_0051250 Human Phenotype Ontology China LOOM
http://purl.obolibrary.org/obo/GO_0051250 Phenotypic Quality Ontology LOOM
http://purl.obolibrary.org/obo/GO_0051250 Cell Ontology LOOM
http://purl.obolibrary.org/obo/GO_0051250 Gene Ontology LOOM