National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Glycine

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C524

ALT_DEFINITION

Amino acid with side chain -H.

A non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter.

CAS_Registry

56-40-6

CHEBI_ID

CHEBI:15428

Chemical_Formula

C2H5NO2

code

C524

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

CRCH

FDA

DEFINITION

A non-essential, non-polar, non-optical, glucogenic amino acid. Glycine, an inhibitory neurotransmitter in the CNS, triggers chloride ion influx via ionotropic receptors, thereby creating an inhibitory post-synaptic potential. In contrast, this agent also acts as a co-agonist, along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors. Glycine is an important component and precursor for many macromolecules in the cells.

FDA_UNII_Code

TE7660XO1C

FULL_SYN

Aminoethanoic acid

Gly

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C79999

label

Glycine

Legacy_Concept_Name

Glycine

NSC_Code

25936

PDQ_Closed_Trial_Search_ID

41347

PDQ_Open_Trial_Search_ID

41347

Preferred_Name

Glycine

prefixIRI

C524

prefLabel

Glycine

Semantic_Type

Amino Acid, Peptide, or Protein

UMLS_CUI

C0017890

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C68442

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29596

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