Preferred Name |
Prolactin |
ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C778 |
ALT_DEFINITION |
A hormone that is made by the pituitary gland (a pea-sized organ in the center of the brain). Prolactin causes a woman's breasts to make milk during and after pregnancy, and has many other effects in the body. |
CAS_Registry |
9002-62-4 |
code |
C778 |
DEFINITION |
Human prolactin (227 aa, 26 kDa precursor) is encoded by the human prolactin (PIT1) gene. This secreted lactogenic glycoprotein is expressed in both anterior pituitary lactotropes and the decidual endometrium. It acts primarily on the mammary gland and, in synergy with estrogen, induces progesterone release by corpus luteum cells to render the uterine mucosa suitable for implantation. |
FULL_SYN |
PRL |
label |
Prolactin |
Legacy_Concept_Name |
Prolactin |
Preferred_Name |
Prolactin |
prefixIRI |
C778 |
prefLabel |
Prolactin |
Semantic_Type |
Hormone |
UMLS_CUI |
C0033371 |
subClassOf |