Ontology for Biomedical Investigations

Last uploaded: January 23, 2019
Preferred Name

plasma cell

Definitions

A terminally differentiated, post-mitotic, antibody secreting cell of the B cell lineage with the phenotype CD138-positive, surface immunonoglobulin-negative, and MHC Class II-negative. Plasma cells are oval or round with extensive rough endoplasmic reticulum, a well-developed Golgi apparatus, and a round nucleus having a characteristic cartwheel heterochromatin pattern and are devoted to producing large amounts of immunoglobulin.

ID

http://purl.obolibrary.org/obo/CL_0000786

editor preferred label

plasma cell

imported from

http://purl.obolibrary.org/obo/cl.owl

label

plasma cell

prefixIRI

CL:0000786

prefLabel

plasma cell

textual definition

A terminally differentiated, post-mitotic, antibody secreting cell of the B cell lineage with the phenotype CD138-positive, surface immunonoglobulin-negative, and MHC Class II-negative. Plasma cells are oval or round with extensive rough endoplasmic reticulum, a well-developed Golgi apparatus, and a round nucleus having a characteristic cartwheel heterochromatin pattern and are devoted to producing large amounts of immunoglobulin.

subClassOf

http://purl.obolibrary.org/obo/CL_0000236

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http://purl.obolibrary.org/obo/BTO_0000392 BRENDA Tissue and Enzyme Source Ontology LOOM
http://purl.bioontology.org/ontology/LNC/LP68360-4 Logical Observation Identifier Names and Codes LOOM
http://purl.obolibrary.org/obo/FMA_70574 Foundational Model of Anatomy LOOM
http://purl.obolibrary.org/obo/CL_0000786 Human Phenotype Ontology China LOOM
http://purl.obolibrary.org/obo/CL_0000786 Human Phenotype Ontology China SAME_URI
http://purl.obolibrary.org/obo/CL_0000786 Cell Ontology LOOM
http://purl.obolibrary.org/obo/CL_0000786 Cell Ontology SAME_URI
http://purl.obolibrary.org/obo/CL_0000786 Cell Line Ontology Subset for Chinese National Infrastructure of Cell Line Resource (NICR) LOOM
http://purl.obolibrary.org/obo/CL_0000786 Cell Line Ontology Subset for Chinese National Infrastructure of Cell Line Resource (NICR) SAME_URI
http://purl.obolibrary.org/obo/CL_0000786 Cell Line Ontology (Chinese Translation) SAME_URI
http://purl.obolibrary.org/obo/CL_0000786 Human Disease Ontology 123 LOOM
http://purl.obolibrary.org/obo/CL_0000786 Human Disease Ontology 123 SAME_URI
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C12486 National Cancer Institute Thesaurus LOOM