Protein Ontology

Last uploaded: January 18, 2022
Preferred Name

interleukin-12 complex

Synonyms

IL-12 complex

Definitions

A protein complex that is composed of an interleukin-12 alpha (p35, product of the IL12A gene) and an interleukin-12 beta subunit (p40, product of the IL12B gene) and is secreted into the extracellular space. Note that this heterodimeric cytokine utilizes the IL-12p35 subunit as its alpha chain, which is also used by IL-35 as its alpha chain, and utilizes the IL-12p40 subunit as its beta chain, which is also used by IL-23 as its beta chain.

ID

http://purl.obolibrary.org/obo/GO_0043514

comment

Note that this heterodimeric cytokine utilizes the IL-12p35 subunit as its alpha chain, which is also used by IL-35 as its alpha chain, and utilizes the IL-12p40 subunit as its beta chain, which is also used by IL-23 as its beta chain.

definition

A protein complex that is composed of an interleukin-12 alpha (p35, product of the IL12A gene) and an interleukin-12 beta subunit (p40, product of the IL12B gene) and is secreted into the extracellular space.

has_exact_synonym

IL-12 complex

has_obo_namespace

cellular_component

id

GO:0043514

label

interleukin-12 complex

notation

GO:0043514

prefLabel

interleukin-12 complex

treeView

http://purl.obolibrary.org/obo/GO_0032991

subClassOf

http://purl.obolibrary.org/obo/GO_0032991

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http://purl.obolibrary.org/obo/GO_0043514 Human Phenotype Ontology China LOOM
http://purl.obolibrary.org/obo/GO_0043514 Human Phenotype Ontology China SAME_URI
http://purl.obolibrary.org/obo/GO_0043514 Gene Ontology LOOM
http://purl.obolibrary.org/obo/GO_0043514 Gene Ontology SAME_URI