loading...| Preferred Name |
Ovarian Follicle |
| Synonyms |
Follicles, Graafian |
| Definitions |
An OOCYTE-containing structure in the cortex of the OVARY. The oocyte is enclosed by a layer of GRANULOSA CELLS providing a nourishing microenvironment (FOLLICULAR FLUID). The number and size of follicles vary depending on the age and reproductive state of the female. The growing follicles are divided into five stages: primary, secondary, tertiary, Graafian, and atretic. Follicular growth and steroidogenesis depend on the presence of GONADOTROPINS. |
| ID |
http://purl.bioontology.org/ontology/MESH/D006080 |
| altLabel |
Follicles, Graafian Follicle, Graafian Graafian Follicles Ovarian Follicles Atretic Follicles Follicle, Atretic Graafian Follicle Atretic Follicle Follicle, Ovarian Follicles, Atretic Follicles, Ovarian |
| AN |
/cytol: consider also THECA CELLS; GRANULOSA CELLS; for follicular development use /physiol, not /growth |
| AQL |
AB AH BS CH CY DE DG EM EN GD IM IN IR ME MI PA PH PP PS RE SU TR UL VI |
| cui |
C1135971 C0018120 C0600225 |
| DC |
1 |
| definition |
An OOCYTE-containing structure in the cortex of the OVARY. The oocyte is enclosed by a layer of GRANULOSA CELLS providing a nourishing microenvironment (FOLLICULAR FLUID). The number and size of follicles vary depending on the age and reproductive state of the female. The growing follicles are divided into five stages: primary, secondary, tertiary, Graafian, and atretic. Follicular growth and steroidogenesis depend on the presence of GONADOTROPINS. A degenerating ovarian follicle as a result of atresia (FOLLICULAR ATRESIA). During atresia, the OOCYTE and GRANULOSA CELLS within the basal lamina die and are replaced by fibrous tissue. The blister-like mature ovarian follicle containing the OVUM surrounded by an accumulation of GRANULOSA CELLS (the cumulus oophorus) and an increasing volume of FOLLICULAR FLUID. The mature Graafian follicle is ready to release the ovum by the process of OVULATION. |
| DX |
19990101 |
| FX |
D010063 D006107 D013799 |
| HN |
99 |
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000201 http://purl.bioontology.org/ontology/MESH/Q000503 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000002 http://purl.bioontology.org/ontology/MESH/Q000528 http://purl.bioontology.org/ontology/MESH/Q000166 http://purl.bioontology.org/ontology/MESH/Q000294 http://purl.bioontology.org/ontology/MESH/Q000254 http://purl.bioontology.org/ontology/MESH/Q000821 http://purl.bioontology.org/ontology/MESH/Q000382 http://purl.bioontology.org/ontology/MESH/Q000601 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000637 http://purl.bioontology.org/ontology/MESH/Q000293 http://purl.bioontology.org/ontology/MESH/Q000098 http://purl.bioontology.org/ontology/MESH/Q000196 http://purl.bioontology.org/ontology/MESH/Q000033 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000000981 |
| Inverse of RO |
http://purl.bioontology.org/ontology/MESH/D013799 |
| Inverse of SIB | |
| Machine permutation |
99; see GRAAFIAN FOLLICLE 1966-98 |
| MDA |
19990101 |
| MMR |
20180630 |
| MN |
A06.300.312.497.535 A05.360.319.114.630.535 |
| notation |
D006080 |
| prefLabel |
Ovarian Follicle |
| TERMUI |
T608652 T018452 T467633 T018453 |
| TH |
NLM (2006) NLM (1966) NLM (2003) NLM (1999) |
| tui |
T023 |
| subClassOf |