| Preferred Name |
diaphragm |
| Synonyms |
phren thoracic diaphragm diaphragm muscle diaphragm of thorax midriff |
| Definitions |
A thin musculomebranous barrier that separates the abdominal and thoracic cavities. Often used for breathing control |
| ID |
http://purl.obolibrary.org/obo/UBERON_0001103 |
| database_cross_reference |
UMLS:C0011980 EV:0100376 FMA:13295 BTO:0000341 OpenCyc:Mx4rvVivz5wpEbGdrcN5Y29ycA EMAPA:17701 GAID:158 MESH:D003964 EFO:0000937 NCIT:C12702 EHDAA2:0003495 VHOG:0000713 MAT:0000502 MA:0001904 CALOHA:TS-0198 http://www.snomedbrowser.com/Codes/Details/181614006 |
| definition |
A thin musculomebranous barrier that separates the abdominal and thoracic cavities. Often used for breathing control |
| development_notes |
originate from the cervical somites, likely C3-C5[PMID:23586979] |
| develops_from | |
| external_definition |
The diaphragm is a skeletal muscle that is responsible for contraction and expansion of the lungs[GO]. |
| function_notes |
breathing control barrier between thoracic and abdominal cavities; stop gastric contents from refluxing into the oesophagus |
| has_exact_synonym |
thoracic diaphragm diaphragm muscle diaphragm of thorax |
| has_obo_namespace |
uberon |
| has_related_synonym |
phren midriff |
| has_relational_adjective |
phrenic |
| homology_notes |
The mammals are characterized by a diaphragm, which separates the thoracic portion of the body cavity from the abdominal region and assists in drawing air into the lungs and forcing it out. Modern reptiles lack a muscular diaphragm and it is reasonable to suppose that the diaphragm developed as a new device that made possible a large degree of oxygen intake for active animals. The change may have taken place during the transition from reptile to mammal (...).[well established][VHOG] |
| id |
UBERON:0001103 |
| immediate transformation of | |
| in_subset |
http://purl.obolibrary.org/obo/uberon/core#uberon_slim http://purl.obolibrary.org/obo/uberon/core#organ_slim |
| innervated_by | |
| label |
diaphragm |
| notation |
UBERON:0001103 |
| prefLabel |
diaphragm |
| taxon_notes |
The urochordate epicardium separates digestive organs from the pharynx and heart, but the anus returns to the upper compartment to discharge wastes through an outgoing siphon (Thoracic_diaphragm#Comparative_anatomy_and_evolution) The existence of some membrane separating the pharynx from the stomach can be traced widely among the chordates. Thus amphioxus possesses an atrium by which water exits the pharynx, which has been argued (and disputed) to be homologous to structures in ascidians and hagfishes.[3] |
| treeView | |
| subClassOf |