loading...| Preferred Name |
submandibular gland |
| Synonyms |
submandibular salivary gland mandibular gland glandula submandibularis maxillary gland submaxillary gland mandibular salivary gland |
| Definitions |
lobular, sexually dimorphic in mouse Either of the paired compound tubuloalveolar (aka tubuloacinar) major salivary glands composed of both serous and mucous secretory cells and situated beneath the mandible. |
| ID |
http://purl.obolibrary.org/obo/UBERON_0001736 |
| comment |
lobular, sexually dimorphic in mouse |
| database_cross_reference |
NCIT:C12233 EV:0100061 UMLS:C0038556 CALOHA:TS-0988 FMA:55093 MESH:D013363 VHOG:0000364 MA:0001589 GAID:942 BTO:0001316 EFO:0001387 EMAPA:18812 http://linkedlifedata.com/resource/umls/id/C0038556 |
| definition |
Either of the paired compound tubuloalveolar (aka tubuloacinar) major salivary glands composed of both serous and mucous secretory cells and situated beneath the mandible. |
| depicted_by |
http://upload.wikimedia.org/wikipedia/commons/5/51/Illu_quiz_hn_02.jpg |
| development_notes |
The submandibular is the first major salivary gland to develop in the embryo, followed by the neighbouring sublingual and then the parotid.[PMID:17336109] |
| develops_from | |
| external_definition |
Either of two major salivary glands situated in the neck near the lower edge of each side of the mandible and emptying into the submandibular duct. [TFD][VHOG] |
| has_exact_synonym |
submandibular salivary gland mandibular gland mandibular salivary gland |
| has_obo_namespace |
uberon |
| has_related_synonym |
glandula submandibularis maxillary gland submaxillary gland |
| homology_notes |
The most common oral glands in mammals are the salivary glands. There are usually three primary pairs of salivary glands, named for their approximate positions: mandibular (submandibular or submaxillary), sublingual, and parotid.[well established][VHOG] |
| id |
UBERON:0001736 |
| in_lateral_side_of | |
| in_subset |
http://purl.obolibrary.org/obo/uberon/core#uberon_slim |
| label |
submandibular gland |
| notation |
UBERON:0001736 |
| part_of | |
| prefLabel |
submandibular gland |
| taxon_notes |
in mice, submandibular gland development initiates as a thickening of the oral epithelium; around E12 an initial (single) epithelial bud on a stalk grows into a condensing neural crest-derived mesenchyme; clefts in the epithelium result in 3-5 epithelial buds at E13.5, and branching morphogenesis occurs with continued proliferation, successive rounds of cleft formation, duct elongation, and duct lumen formation, so that by E14 the gland is highly branched (multi-lobed); functional differentiation, with the appearance of proacinar cells and secretory products begins after E15 and continues to birth; acinar differentiation continues postnatally with final differentiation of the granular convoluted tubules at puberty[MGI:anna] In humans, they account for 70% of the salivary volume and weigh about 15 grams. [WP,unvetted] In mouse, multilobed and lobulated, on the ventral midline of the neck |
| terminology_notes |
The term submandibular as used in humans, is incorrect due the difference in topography of these structures[http://www.avdc.org] |
| treeView | |
| subClassOf |