loading...| Preferred Name |
spleen |
| Synonyms |
lien |
| Definitions |
the organ that functions to filter blood and to store red corpuscles and platelets |
| ID |
http://purl.obolibrary.org/obo/UBERON_0002106 |
| database_cross_reference |
EV:0100055 MIAA:0000085 UMLS:C0037993 CALOHA:TS-0956 MA:0000141 GAID:1289 MESH:A15.382.520.604.713 NCIT:C12432 OpenCyc:Mx4rvVjgw5wpEbGdrcN5Y29ycA VHOG:0000120 galen:Spleen FMA:7196 EMAPA:18767 MAT:0000085 TAO:0000436 EFO:0000869 XAO:0000328 BTO:0001281 ZFA:0000436 AAO:0010395 http://www.snomedbrowser.com/Codes/Details/181279003 |
| definition |
the organ that functions to filter blood and to store red corpuscles and platelets |
| depicted_by |
http://upload.wikimedia.org/wikipedia/commons/d/d6/Illu_spleen.jpg |
| develops_from | |
| external_definition |
An organ involved in red blood cell filtration and immune response.[AAO] |
| function_notes |
It synthesizes antibodies in its white pulp and removes, from blood and lymph node circulation, antibody-coated bacteria along with antibody-coated blood cells |
| has_obo_namespace |
uberon |
| has_related_synonym |
lien |
| has_relational_adjective |
splenic lienal |
| homology_notes |
With the advent of clonal selection, the accumulation and segregation of T and B cells in specialized organs for antigen presentation became necessary, and indeed the spleen is found in all jawed vertebrates, but not in agnathans or invertebrates.[well established][VHOG] |
| id |
UBERON:0002106 |
| in_subset |
http://purl.obolibrary.org/obo/uberon/core#uberon_slim http://purl.obolibrary.org/obo/uberon/core#organ_slim http://purl.obolibrary.org/obo/uberon/core#pheno_slim |
| label |
spleen |
| notation |
UBERON:0002106 |
| prefLabel |
spleen |
| taxon_notes |
In humans, it is located in the left upper quadrant of the abdomen. It removes old red blood cells and holds a reserve in case of hemorrhagic shock, especially in animals like horses (not in humans), while recycling iron Neither hagfish nor lampreys possess what might be considered a discrete and condensed spleen. Hagfish possess dispersed lymphoid tissue within the submucosa of the intestine (96) associated with the portal vein (97), whereas lymphoid tissue is associated with the typhlosole portion of the intestine in lampreys (96) |
| treeView | |
| subClassOf |
http://purl.obolibrary.org/obo/UBERON_0005057 http://purl.obolibrary.org/obo/UBERON_0004177 |
| disjointWith |