loading...| Preferred Name |
pronephros |
| Synonyms |
archinephron pronephric kidney pronephron embryonic kidney |
| Definitions |
Once the more complex mesonephros forms the pronephros undergoes apoptosis in amphibians. In fishes the nephron degenerates but the organ remains and becomes a component of the immune system[Wikipedia:Pronephros]. // TODO - check developmental relationships. Note that we previously include the ZFA/XAO terms under the more specific 'pronephric kidney', but these are now merged. TODO GCI: relationship: capable_of GO:0030104 In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensible for larval life[GO]. |
| ID |
http://purl.obolibrary.org/obo/UBERON_0002120 |
| comment |
Once the more complex mesonephros forms the pronephros undergoes apoptosis in amphibians. In fishes the nephron degenerates but the organ remains and becomes a component of the immune system[Wikipedia:Pronephros]. // TODO - check developmental relationships. Note that we previously include the ZFA/XAO terms under the more specific 'pronephric kidney', but these are now merged. TODO GCI: relationship: capable_of GO:0030104 |
| database_cross_reference |
EHDAA:1017 EHDAA2:0001570 FMA:72170 NCIT:C34280 MIAA:0000117 EMAPA:16579 XAO:0002000 UMLS:C0231048 ZFA:0000151 AAO:0011089 TAO:0000151 VHOG:0000037 BTO:0001541 EFO:0000927 MAT:0000117 http://linkedlifedata.com/resource/umls/id/C0231048 |
| definition |
In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensible for larval life[GO]. |
| develops_from | |
| external_definition |
A kidney formed of nephric tubules arising in the anterior region of the nephric ridge; forms only as a transient embryonic structure. [Evolution, Fourth_Edition_(2006)_McGraw-Hill, Function, Kardong_KV, Vertebrates:_Comparative_Anatomy, p.748][VHOG] Organ that serves as a transient kidney, providing osmoregulation during early developmental stages and then degenerating during metamorphosis.[AAO] The embryonic kidney, present at the level of the third somite, is composed of two glomeruli fused at the midline, two pronephric tubules, and paired bilateral pronephric ducts that modify the composition of the blood filtrate before delivering it to the cloaca for excretion.Kimmel et al, 1995.[TAO] |
| has_alternative_id |
UBERON:0005794 |
| has_exact_synonym |
pronephric kidney |
| has_obo_namespace |
uberon |
| has_related_synonym |
archinephron pronephron embryonic kidney |
| has_relational_adjective |
pronephric |
| homology_notes |
In all vertebrate embryos, the kidney begins with the differentiation of a few renal tubules from the anterior end of the nephric ridge overlying the pericardial cavity. (...) This early-developing embryonic kidney is called the pronephros.[well established][VHOG] |
| id |
UBERON:0002120 |
| in_subset |
http://purl.obolibrary.org/obo/uberon/core#uberon_slim |
| label |
pronephros |
| located_in | |
| notation |
UBERON:0002120 |
| prefLabel |
pronephros |
| treeView | |
| subClassOf |
http://purl.obolibrary.org/obo/UBERON_0002113 |